Anti-PD-L1 Antibody

Anti-PD-L1 Antibodyis available at Gentaur for Next week Delivery.

Description: Programmed death 1 ligand 1 (PD-L1) also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. B7-H1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. PD-L1 is highly expressed in the heart, skeletal muscle, placenta and lung and weakly expressed in the thymus, spleen, kidney and liver. PD-L1 is expressed on activated T-cells, B-cells, dendritic cells, keratinocytes and monocytes. PD-L1 is up-regulated on T- and B-cells, dendritic cells, keratinocytes and monocytes after LPS and IFNG activation and up-regulated in B-cells activated by surface Ig cross-linking. PD-L1 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.

Immunogen Sequence:Recombinant human PD-L1

Target Alternative Name:PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect PD-L1 in human samples

Formulation:In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% Proclin

Purification: Affinity purified

Application:WB

Positive Control:WB: PD-L1 human recombinant

Application And Usages:WB: 1-4 µg

Handling:The antibody solution should be gently mixed before use