Anti-PAD4 Polyclonal Antibody

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SKU:
A2324-100
  • Anti-PAD4 Polyclonal Antibody
  • Anti-PAD4 Polyclonal Antibody
€375
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Description

Anti-PAD4 Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Protein arginine deiminases (PADs) are a family of guanidine-modifying enzymes that catalyze the post-translational modification of target proteins by converting arginine to citrulline. Excessive citrullination of proteins may result in disease states. PAD4 (also known as PADI5) is expressed in neutrophils and in a variety of tissues. PAD4 is known to citrullinate histones, which initiates chromatin decondensation in neutrophils and the subsequent release of neutrophil extracellular traps (NETs), which leads to a lytic form of cell death known as NETosis. The presence of serum PAD4 autoantibodies has been associated with rheumatoid arthritis.

Immunogen Sequence:Recombinant full length protein of human PAD4

Target Alternative Name:Peptidyl Arginine Deiminase 4; PDI5; Peptidyl Arginine Deiminase, Type IV; Peptidyl Arginine Deiminase, Type V; Protein-Arginine Deiminase Type IV; Protein-Arginine Deiminase Type-4; EC 3.5.3.15; HL-60 PAD; PADI5; PDI4; PAD; Peptidylarginine Deiminase IV; PADI-H Protein; PADI4

Species Reactivities:Human Rat

Tag Line:Protein arginine deiminase associated with rheumatoid arthritis

Formulation:in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide

Purification: Immunogen affinity chromatography

Application:Immunofluorescence (IF) Immunohistochemistry (IHC) Western Blotting

Positive Control:/

Application And Usages:/

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µg
Antibody Target:
Human PAD4
Category:
GM-CSF
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
Q9UM07
Gene Id:
23569
Appearance:
Liquid
Form:
Rabbit polyclonal
Storage Condition:
-20ºC
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
FAUX
Immunocytochemistry Verified:
VRAI
Immunofluorescence Verified:
FAUX
Immunoprecipitation Verified:
VRAI
FACS Verified:
FAUX
ELISA Verified:
FAUX
ChIP Verified:
VRAI
Dot Blot Verified:
FAUX
Flow Cytometry Verified:
FAUX
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