Anti-MMP-8 Antibody

Anti-MMP-8 Antibodyis available at Gentaur for Next week Delivery.

Description: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. Unlike other members of the MMP family, MMP-8 is expressed exclusively in inflammatory conditions. MMP-8 is also the predominant collagenase expressed in ulcers and healing wounds.

Immunogen Sequence:Synthetic peptide surrounding amino acid 448 of rat MMP-8

Target Alternative Name:MMP8 ,120355 , P22894 , CLG1 , HNC, PMNL-CL , EC 3.4.24.34 , MMP-8 , Matrix metalloproteinase

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:In phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (1-4 µg/ml). Other applications have not been tested. Blocking peptide (Cat.# 3528RBP-50) is available separately. The antibody recognizes latent (85 kDa) and active forms (25-65 kDa) of MMP8 from human, mouse, and rat origins.

Handling:The antibody solution should be gently mixed before use.