MMP-8 Antibody

MMP-8 Antibodyis available at Gentaur for Next week Delivery.

Description: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. Unlike other members of the MMP family, MMP-8 is expressed exclusively in inflammatory conditions. MMP-8 is also the predominant collagenase expressed in ulcers and healing wounds.

Immunogen Sequence:Synthetic peptide mapping to the hinge region of the human MMP-8 sequence

Target Alternative Name:120355 , P22894 , CLG1 , HNC, PMNL-CL , EC 3.4.24.34 , MMP-8 , Matrix metalloproteinase

Species Reactivities:Human, mouse, rat

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Formulation:100 µg (0.5 mg/ml) protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation, Immunohistochemistry

Positive Control:/

Application And Usages:Western blotting (1-4 µg/ml), immunoprecipitation (10-20 µg/ml), and Immunohistochemistry (15-25 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes latent (85 kDa) and active forms (25-65 kDa) of MMP8 from human, mouse, and rat origins.

Handling:The antibody solution should be gently mixed before use.