Anti-IL-23α (Tildrakizumab), Humanized Antibody

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SKU:
A2159-100
€455
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Description

Anti-IL-23α (Tildrakizumab), Humanized Antibodyis available at Gentaur for Next week Delivery.

Description: The research-grade biosimilar is a humanized IgG1 monoclonal antibody that specifically targets the p19 subunit of IL-23 and thereby inhibits the interaction with the IL-23 receptor. IL-23 is a cytokine that plays an important role in mediating inflammatory and immune responses. Binding of the antibody to Il-23 blocks the release of pro-inflammatory cytokines and chemokines associated with psoriasis. The original drug received approval from the FDA in 2018 to treat patients with moderate-to-severe plaque psoriasis who are candidates for systemic and phototherapy

Immunogen Sequence:Human IL-23α

Target Alternative Name:MK-3222, SCH 900222, P19, SGRF, IL-23, IL23A, IL23P19

Species Reactivities:Human

Tag Line:The biosimilar is a humanized monoclonal antibody that specifically targets IL-23 p19 subunit and inhibits the release of cytokines and chemokines involved in mediating inflammation in psoriasis

Formulation:In PBS, pH 7.5

Purification: Protein A purified

Application:/

Positive Control:/

Application And Usages:/

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µg
Antibody Target:
IL-23α
Category:
Biosimilars
Host:
Recombinant
Antibody Type:
Monoclonal
Isotype:
IgG1, kappa
Accession Number:
DB14004
Concentration:
1 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-80ºC
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
FAUX
Immunocytochemistry Verified:
FAUX
Immunofluorescence Verified:
FAUX
Immunoprecipitation Verified:
FAUX
FACS Verified:
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ELISA Verified:
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ChIP Verified:
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Dot Blot Verified:
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Flow Cytometry Verified:
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