Anti-IL-17α (Ixekizumab), Humanized Antibody

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SKU:
A2149-100
€455
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Description

Anti-IL-17α (Ixekizumab), Humanized Antibodyis available at Gentaur for Next week Delivery.

Description: The research-grade biosimilar is a humanized IgG4 monoclonal antibody that targets IL-17α and prevents the interaction with its receptor (IL-17R), thus blocking IL-17α mediated inflammatory and immune responses. IL-17α is known to play an important role in autoimmune diseases such as rheumatoid arthritis and plaque psoriasis. The monoclonal antibody is produced in CHO cells using recombinant DNA technology. It consists of two identical light chains of 219 amino acids each and two identical heavy chains of 445 amino acids each. The original monoclonal antibody received approval from the FDA for the treatment of adults suffering from moderate-to-severe psoriasis and psoriatic arthritis

Immunogen Sequence:Human IL-17α

Target Alternative Name:IL17a, IL17, CTLA8, IL-17, CTLA-8, IL-17A

Species Reactivities:Human

Tag Line:A humanized monoclonal antibody that specifically targets IL-17α and inhibits IL-17α mediated inflammatory responses

Formulation:In PBS, pH 7.5

Purification: Protein A purified

Application:/

Positive Control:/

Application And Usages:/

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µg
Antibody Target:
IL-17α
Category:
Biosimilars
Host:
Recombinant
Antibody Type:
Monoclonal
Isotype:
IgG4, kappa
Accession Number:
DB11569
Concentration:
Lot specific
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-80ºC
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
FAUX
Immunocytochemistry Verified:
FAUX
Immunofluorescence Verified:
FAUX
Immunoprecipitation Verified:
FAUX
FACS Verified:
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ELISA Verified:
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ChIP Verified:
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Dot Blot Verified:
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Flow Cytometry Verified:
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