Description
Anti-IL-23α (Tildrakizumab), Humanized Antibodyis available at Gentaur for Next week Delivery.
Description: The research-grade biosimilar is a humanized IgG1 monoclonal antibody that specifically targets the p19 subunit of IL-23 and thereby inhibits the interaction with the IL-23 receptor. IL-23 is a cytokine that plays an important role in mediating inflammatory and immune responses. Binding of the antibody to Il-23 blocks the release of pro-inflammatory cytokines and chemokines associated with psoriasis. The original drug received approval from the FDA in 2018 to treat patients with moderate-to-severe plaque psoriasis who are candidates for systemic and phototherapy
Immunogen Sequence:Human IL-23α
Target Alternative Name:MK-3222, SCH 900222, P19, SGRF, IL-23, IL23A, IL23P19
Species Reactivities:Human
Tag Line:The biosimilar is a humanized monoclonal antibody that specifically targets IL-23 p19 subunit and inhibits the release of cytokines and chemokines involved in mediating inflammation in psoriasis
Formulation:In PBS, pH 7.5
Purification: Protein A purified
Application:/
Positive Control:/
Application And Usages:/
Handling:The antibody solution should be gently mixed before use.
Additional Information
Size: |
100 µg |
Antibody Target: |
IL-23α |
Category: |
Biosimilars |
Host: |
Recombinant |
Antibody Type: |
Monoclonal |
Isotype: |
IgG1, kappa |
Accession Number: |
DB14004 |
Concentration: |
1 mg/ml |
Appearance: |
Colorless liquid |
Form: |
Liquid |
Storage Condition: |
-80ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |
Country of Animal Origin: |
USA |
Country of Manufacture: |
USA |
Usage: |
For Research Use Only! Not to be used in humans. |
Western Blot Verified: |
FAUX |
Immunocytochemistry Verified: |
FAUX |
Immunofluorescence Verified: |
FAUX |
Immunoprecipitation Verified: |
FAUX |
FACS Verified: |
FAUX |
ELISA Verified: |
FAUX |
ChIP Verified: |
FAUX |
Dot Blot Verified: |
FAUX |
Flow Cytometry Verified: |
FAUX |