Anti-IL-23α (Guselkumab), Human IgG1 Antibody

Anti-IL-23α (Guselkumab), Human IgG1 Antibodyis available at Gentaur for Next week Delivery.

Description: Guselkumab is a fully human IgG1 lambda monoclonal antibody that is produced in Chinese Hamster Ovary (CHO) cells. This monoclonal antibody selectively inhibits IL-23 by binding to the p19 subunit of IL-23, blocking its interaction with the receptor (IL-23R), and inhibiting the release of proinflammatory chemokines and cytokines. The antibody was developed by Janssen Biotech and received FDA approval for the treatment of moderate to severe plaque psoriasis. Guselkumab is marketed under the trade name TREMFYA®

Immunogen Sequence:Guselkumab

Target Alternative Name:CNTO1959, CNTO-1959, TREMFYA, IL23α, IL 23α

Species Reactivities:Human

Tag Line:Guselkumab is a human monoclonal antibody that selectively targets IL-23 and blocks the interaction with its receptor (IL-23R), thereby inhibiting IL-23 mediated signaling. This monoclonal antibody received FDA approval to treat moderate to severe plaque psoriasis

Formulation:In PBS, pH 7.5

Purification: Protein A purified

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Handling:The antibody solution should be gently mixed before use.