Description
Anti-IL-17α (Ixekizumab), Humanized Antibodyis available at Gentaur for Next week Delivery.
Description: The research-grade biosimilar is a humanized IgG4 monoclonal antibody that targets IL-17α and prevents the interaction with its receptor (IL-17R), thus blocking IL-17α mediated inflammatory and immune responses. IL-17α is known to play an important role in autoimmune diseases such as rheumatoid arthritis and plaque psoriasis. The monoclonal antibody is produced in CHO cells using recombinant DNA technology. It consists of two identical light chains of 219 amino acids each and two identical heavy chains of 445 amino acids each. The original monoclonal antibody received approval from the FDA for the treatment of adults suffering from moderate-to-severe psoriasis and psoriatic arthritis
Immunogen Sequence:Human IL-17α
Target Alternative Name:IL17a, IL17, CTLA8, IL-17, CTLA-8, IL-17A
Species Reactivities:Human
Tag Line:A humanized monoclonal antibody that specifically targets IL-17α and inhibits IL-17α mediated inflammatory responses
Formulation:In PBS, pH 7.5
Purification: Protein A purified
Application:/
Positive Control:/
Application And Usages:/
Handling:The antibody solution should be gently mixed before use.
Additional Information
Size: |
100 µg |
Antibody Target: |
IL-17α |
Category: |
Biosimilars |
Host: |
Recombinant |
Antibody Type: |
Monoclonal |
Isotype: |
IgG4, kappa |
Accession Number: |
DB11569 |
Concentration: |
Lot specific |
Appearance: |
Colorless liquid |
Form: |
Liquid |
Storage Condition: |
-80ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |
Country of Animal Origin: |
USA |
Country of Manufacture: |
USA |
Usage: |
For Research Use Only! Not to be used in humans. |
Western Blot Verified: |
FAUX |
Immunocytochemistry Verified: |
FAUX |
Immunofluorescence Verified: |
FAUX |
Immunoprecipitation Verified: |
FAUX |
FACS Verified: |
FAUX |
ELISA Verified: |
FAUX |
ChIP Verified: |
FAUX |
Dot Blot Verified: |
FAUX |
Flow Cytometry Verified: |
FAUX |