Anti-Histone H3 pan, Rabbit Monoclonal Antibody

Anti-Histone H3 pan, Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code”. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.

Immunogen Sequence:A peptide corresponding to the C-terminus of human Histone H3

Target Alternative Name:H3F3A, H3.3A, H3F3, H3F3B, H3.3B

Species Reactivities:Human

Tag Line:Rabbit monoclonal antibody to detect Histone H3

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified using protein A

Application:WB, ELISA, Multiplex, ICC

Positive Control:WB: A375, HEK293, HeLa and SK-MEL-2 whole cell lysates, ICC: Hela cells, ELISA: Hela cells

Application And Usages:Western Blot: 0.01 µg/ml – 0.25 µg/ml; ICC: 1 µg/ml - 5 µg/ml; ELISA: 0.2 µg/ml - 1 µg/ml; Multiplex: 0.1 µg/ml – 0.5 µg/ml

Handling:The antibody solution should be gently mixed before use.