Anti- Histone H2AZ, Rabbit Monoclonal Antibody

Anti- Histone H2AZ, Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

Immunogen Sequence:A peptide corresponding to the C-terminus of human Histone H2AZ

Target Alternative Name:Histone H2A.Z, H2A/z, H2AFZ

Species Reactivities:Human

Tag Line:Rabbit monoclonal antibody to detect Histone H2AZ

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified using protein A

Application:WB, ICC, ELISA, Multiplex

Positive Control:WB: HeLa, HEK293, A375, SK-MEL-2 and A431; ICC: Hela cells

Application And Usages:WB: 0. 1 µg/mL – 0.5 µg/mL; ICC: 1 µg/mL - 2 µg/mL; ELISA: 0.1 µg/mL - 1 µg/mL; Multiplex: 0.1 µg/mL – 1 µg/mL.

Handling:The antibody solution should be gently mixed before use.