Anti-CoV-2, MERS & SARS-CoV NP Mouse IgG1 Antibody

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SKU:
A2063-100
€255
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Description

Anti-CoV-2, MERS & SARS-CoV NP Mouse IgG1 Antibodyis available at Gentaur for Next week Delivery.

Description: SARS-CoV-2, MERS-CoV and SARS-CoV belong to the family of Coronaviridae and are characterized by large positive-sense RNA genome, that is about 28 - 30 kb in length. One unique feature of SARS-CoV-2, SARS-CoV and MERS-CoV is that two-thirds of the viral genome is translated into two large polyproteins whereas the remaining viral genome is transcribed into sub-genomic RNAs. The two large polyproteins encode multiple non-structural proteins that play an important role in viral replication and transcription. SARS-CoV-2, SARS-CoV and MERS-CoV transcribe multiple sub-genomic RNAs that encode four structural proteins, namely, envelope (E), membrane (M), spike (S), and nucleocapsid (N). Some of the main functions of the nucleocapsid protein are 1) to package the genomic of the virus into long and helical ribonucleoprotein (RNP) complexes, 2) to dimerize and associate with genomic RNA of the virus, as well as interact with other structural proteins of the virus, both of which functions are essential for viral assembly, 3) associate with ER-Golgi complex during virus budding, 4) assist in genomic RNA synthesis, 5) assist RNA chaperone proteins in proper folding of nucleic acids, and 6) play an important role in viral pathogenesis.

Immunogen Sequence:Recombinant Coronavirus Nucleoprotein peptide

Target Alternative Name:/

Species Reactivities:Human

Tag Line:Purified mouse monoclonal antibody to detect SARS-CoV-2, MERS and SARS Coronavirus Nucleoprotein. Has no crossreactivity with Coronavirus OC43, NL63 and 229E

Formulation:In 10 mM PBS, pH 7.2, 0.1% sodium azide

Purification: Affinity purified using protein A

Application:Immunofluorescence (IF),ELISA

Positive Control:/

Application And Usages:ELISA, IF

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µg
Antibody Target:
SARS-CoV-2, MERS & SARS-CoV NP
Category:
Primary antibody
Host:
Mouse
Antibody Type:
Monoclonal
Isotype:
IgG1
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
2-8°C (Short term), -20°C (Long term)
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
False
Immunocytochemistry Verified:
False
Immunofluorescence Verified:
True
Immunoprecipitation Verified:
False
FACS Verified:
False
ELISA Verified:
True
ChIP Verified:
False
Dot Blot Verified:
False
Flow Cytometry Verified:
False
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