Anti-CD35 / CR1 Antibody (E11)

Anti-CD35 / CR1 Antibody (E11)is available at Gentaur for Next week Delivery.

Description: Recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This mAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This mAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This mAb labels follicular dendritic cells and follicular dendritic cell sarcoma.

Immunogen Sequence:Intact human monocytes

Target Alternative Name:C3 binding protein, C3b/C4b receptor, C3BR, C4BR, Complement Component (3b/4b) receptor 1 including Knops blood group system, Complement receptor type 1, KN, Knops blood group antigen

Species Reactivities:Human, Baboon, Cynomolgus Monkey, Rhesus Monkey

Tag Line:Monoclonal Antibody to detect CD35 / CR1 in human, Baboon, Cynomolgus Monkey, Rhesus Monkey samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Tonsil

Application And Usages:FC: 0.5-1 µg/1X106 cells in 0.1ml, IF: 1-2 µg/ml, IHC: 0.5-1 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use