Anti-CD20 Rabbit Monoclonal Antibody

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SKU:
A1594-50
£208.54
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Description

Anti-CD20 Rabbit Monoclonal Antibody is available at Gentaur for Next week Delivery.

Description: It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This mAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.

Immunogen Sequence:A peptide corresponding to the C-terminus of human CD20

Target Alternative Name:B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect CD20 in human samples.

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified

Application:WB, IHC

Positive Control:WB: Raji cell lysate; IHC: human tonsil tissue

Application And Usages:WB: 1:1000-1:2000, IHC: 1:500-1:1000

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
50 µl
Antibody Target:
CD20
Category:
CD Antigen
Host:
Rabbit
Antibody Type:
Monoclonal
Isotype:
Rabbit IgG
Accession Number:
P11836
Gene Id:
931
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20°C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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