Anti-CD20 Rabbit Monoclonal Antibody

Anti-CD20 Rabbit Monoclonal Antibody is available at Gentaur for Next week Delivery.

Description: It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This mAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.

Immunogen Sequence:A peptide corresponding to the C-terminus of human CD20

Target Alternative Name:B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect CD20 in human samples.

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified

Application:WB, IHC

Positive Control:WB: Raji cell lysate; IHC: human tonsil tissue

Application And Usages:WB: 1:1000-1:2000, IHC: 1:500-1:1000

Handling:The antibody solution should be gently mixed before use.