Anti-Caspase-3 Rabbit Monoclonal Antibody

Anti-Caspase-3 Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-3 is synthesized as an inactive pro-enzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP and DFF).

Immunogen Sequence:Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-3 is synthesized as an inactive pro-enzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP and DFF).

Target Alternative Name:CPP32, CASP3, apopain, procaspase3, CPP32B, SCA-1, CPP-32, Apopain, Yama

Species Reactivities:Human

Tag Line:Rabbit monoclonal antibody to detect Caspase-3 in human samples.

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified using protein A

Application:IHC, WB

Positive Control:WB: Jurkat cell lysates; IHC: human breast cancer tissues

Application And Usages:IHC: 1:1000 -1:2500 dilution; WB: 1:1000 - 1:2000 dilution

Handling:The antibody solution should be gently mixed before use.