Anti-Caspase-3 Antibody

Anti-Caspase-3 Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Immunogen Sequence:Recombinant protein of human CASP3

Target Alternative Name:CASP3, Caspase 3, apoptosis-related cysteine protease, CPP32B, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1

Species Reactivities:Rat, Mouse, Human

Tag Line:Polyclonal antibody to detect Caspase-3 in human mouse and rat sample.

Formulation:PBS with 0.05% sodium azide, 50% glycerol, PH7.3

Purification: Affinity purification

Application:Immunohistochemistry (IHC), Western Blotting, ELISA

Positive Control:/

Application And Usages:WB 1:200-1:1000, IHC 1:50-1:200

Handling:The antibody solution should be gently mixed before use.