AMPK⍺1 Antibody

AMPK⍺1 Antibodyis available at Gentaur for Next week Delivery.

Description: AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.

Immunogen Sequence:Synthetic peptide surroundign amino acid 486 of human AMPK alpha 1

Target Alternative Name:5'-AMP-activated protein kinase, AMPK catalytic alpha-1 chain, AMPK alpha-1 chain

Species Reactivities:Human, mouse, rat

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti-AMPKa1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal

Purification: Affinity purified

Application:Western blot

Positive Control:Jurkat cell lysate

Application And Usages:The antibody can be used for Western blotting (1–4 µg/ml).

Handling:The antibody solution should be gently mixed before use.