AMPK⍺2 Antibody

AMPK⍺2 Antibodyis available at Gentaur for Next week Delivery.

Description: AMPK2 alpha2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (H mgCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart sμggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Immunogen Sequence:KLH conjugated synthetic peptide between 476-507 amino acids from the C-terminal region of human AMPK alpha2.

Target Alternative Name:5'-AMP-activated protein kinase, catalytic subunit alpha-2, AMPK alpha-2 chain

Species Reactivities:Human, mouse

Tag Line:/

Formulation:100 µg (1 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Purification: Ammonium sulphate precipitated

Application:Western blot

Positive Control:/

Application And Usages:The antibody can be used for and Western blotting (1:1000 dilution).

Handling:The antibody solution should be gently mixed before use.