Urokinase

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SKU:
4793-100
€185
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Description

Urokinase is available at Gentaur for Next week delivery.

A serine protease which activates zymogen

Biomolecule/Target:

Alternates names: Urokinase, Abbokinase, Urokinase-type Plasminogen Activator,uPA, EC 3.4.21.73, UK.

Synonyms: Urokinase, Abbokinase, Urokinase-type Plasminogen Activator,uPA, EC 3.4.21.73, UK.

Background Information: Urokinase (UK) is a serine protease, which is one of biological plasminogen activators. It is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. It can be obtained from human urine or kidney cell culture. UK is a two-chain glycoprotein containing 411 amino acids with 12 dissulfide bonds. Its molecular weight is 54,000.

Reconstitution Instructions: Reconstitute in sterile H₂O to a concentration >100 μg/ml. The solution can then be diluted into other aqueous solutions.

NCBI Gene Symbol:

Gene ID:

NCBI Accession:

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
No
Source:
Human urine
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
≥90%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
1 nM UK will cause a change in absorbance of 0.001 at 405 nm in 1 minute at R/T in 100 µl reaction mixture containing 0.05 M Tris-HCl, 0.1 M NaCl, pH 7.4, using S2444 (0.6mM) as the substrate.
Biological activity:
N/A
Results:
N/A
Molecular Weight:
54.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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