Description
Ubiquitin-AMC is available at Gentaur for Next week delivery.
An industry standard substrate for deubiquitinylating enzymes (DUBs)
Biomolecule/Target:
Alternates names: Ubiquitin-Aminomethylcoumarin
Synonyms: Ubiquitin-Aminomethylcoumarin
Background Information: Prepared by the C-terminal derivatisation of ubiquitin with 7-amino-4-methylcoumarin. Acts as a useful and sensitive fluorogenic substrate for a wide range of deubiquitinylating enzymes (DUBs), including ubiquitin C-terminal hydrolases (UCHs) and ubiquitin specific proteases (USPs). Ubiquitin-AMC has been shown to be a sensitive substrate for UCH-L3 (Km = 0.039μM) and for Isopeptidase-T (Km = 0.17-1.4μM), as well as for studying deubiquitinylating activity where detection sensitivity or continuous monitoring of activity is essential.
Reconstitution Instructions: N/A
NCBI Gene Symbol:
Additional Information
Size: |
25 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Purity by SDS-PAGE: |
N/A |
Purity: |
≥95% |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
8.6 Kda |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
1 mg/ml (DMSO) |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |