Description
Ubiquitin Aldehyde, human recombinant is available at Gentaur for Next week delivery.
An inhibitor of deubiquitinylating enzymes (DUBs)
Biomolecule/Target:
Alternates names: Ubiquitin Aldehyde
Synonyms: Ubiquitin Aldehyde
Background Information: Ubiquitin-Aldehyde is a potent and specific inhibitor of deubiquitinating enzymes (DUBs) based on a C-terminal electrophilic Aldehyde group. Ub-Aldehyde can be used for activity profiling experiments and DUB inhibitor specificity determination. It targets four of the five major DUB families: UCH, USP, OUT, and MJD, while leaving JAMM metalloproteases uninhibited. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human Ubiquitin-Aldehyde concentration of 1-5 μM.
Reconstitution Instructions: N/A
NCBI Gene Symbol: N/A
Gene ID: N/A
NCBI Accession: N/A
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
N/A |
Assay: |
SDS-PAGE |
Purity: |
≥97% |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
UCHL3 activity with Ubiquitin-AMC measured in the presence of 17.5 nM and 0.1 nM Ubiquitin Aldehyde. |
Biological activity: |
UCHL3 activity with Ubiquitin-AMC measured in the presence of 17.5 nM and 0.1 nM Ubiquitin Aldehyde. |
Results: |
N/A |
Molecular Weight: |
8.6 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
350 uM, 3.1 mg/mL |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |