Ubiquitin Aldehyde, human recombinant

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SKU:
4845-50
€185
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Description

Ubiquitin Aldehyde, human recombinant is available at Gentaur for Next week delivery.

An inhibitor of deubiquitinylating enzymes (DUBs)

Biomolecule/Target:

Alternates names: Ubiquitin Aldehyde

Synonyms: Ubiquitin Aldehyde

Background Information: Ubiquitin-Aldehyde is a potent and specific inhibitor of deubiquitinating enzymes (DUBs) based on a C-terminal electrophilic Aldehyde group. Ub-Aldehyde can be used for activity profiling experiments and DUB inhibitor specificity determination. It targets four of the five major DUB families: UCH, USP, OUT, and MJD, while leaving JAMM metalloproteases uninhibited. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human Ubiquitin-Aldehyde concentration of 1-5 μM.

Reconstitution Instructions: N/A

NCBI Gene Symbol: N/A

Gene ID: N/A

NCBI Accession: N/A

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
N/A
Assay:
SDS-PAGE
Purity:
≥97%
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
UCHL3 activity with Ubiquitin-AMC measured in the presence of 17.5 nM and 0.1 nM Ubiquitin Aldehyde.
Biological activity:
UCHL3 activity with Ubiquitin-AMC measured in the presence of 17.5 nM and 0.1 nM Ubiquitin Aldehyde.
Results:
N/A
Molecular Weight:
8.6 kDa
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
350 uM, 3.1 mg/mL
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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