Description
Ubiquitin Aldehyde, human recombinant is available at Gentaur for Next week delivery.
An inhibitor of deubiquitinylating enzymes (DUBs)
Biomolecule/Target:
Alternates names: Ubiquitin Aldehyde
Synonyms: Ubiquitin Aldehyde
Background Information: Ubiquitin-Aldehyde is a potent and specific inhibitor of deubiquitinating enzymes (DUBs) based on a C-terminal electrophilic Aldehyde group. Ub-Aldehyde can be used for activity profiling experiments and DUB inhibitor specificity determination. It targets four of the five major DUB families: UCH, USP, OUT, and MJD, while leaving JAMM metalloproteases uninhibited. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human Ubiquitin-Aldehyde concentration of 1-5 μM.
Reconstitution Instructions: N/A
NCBI Gene Symbol: N/A
Gene ID: N/A
NCBI Accession: N/A
Additional Information
| Size: | 50 μg | 
| Country of Manufacturing Origin: | USA | 
| Country of Animal Origin: | USA | 
| Gene Source: | Human | 
| Recombinant: | Yes | 
| Source: | E. coli | 
| Purity by SDS-PAGE: | N/A | 
| Assay: | SDS-PAGE | 
| Purity: | ≥97% | 
| Assay 2: | N/A | 
| Endotoxin Level: | N/A | 
| Activity (Specifications/test method): | UCHL3 activity with Ubiquitin-AMC measured in the presence of 17.5 nM and 0.1 nM Ubiquitin Aldehyde. | 
| Biological activity: | UCHL3 activity with Ubiquitin-AMC measured in the presence of 17.5 nM and 0.1 nM Ubiquitin Aldehyde. | 
| Results: | N/A | 
| Molecular Weight: | 8.6 kDa | 
| Storage Temperature: | -80°C | 
| Shelf Life: | 12 months | 
| Concentration: | 350 uM, 3.1 mg/mL | 
| Appearance: | Liquid | 
| Handling: | Centrifuge the vial prior to opening. | 
 
             
             
             
             
             
            