UbcH5a, human recombinant (His-tag)

UbcH5a, human recombinant (His-tag) is available at Gentaur for Next week delivery.

An essential ubiquitin-conjugating enzyme

Biomolecule/Target:

Alternates names: UbcH5a, Ubiquitin conjugating enzyme H5a, Ubiquitin conjugating enzyme, Ubiquitin-conjugating enzyme E2 D1, Stimulator of Fe transport, UBC4/5 homolog, UbcH5, Ubiquitin carrier protein D1, Ubiquitin-conjugating enzyme E2(17)KB 1, Ubiquitin-conjugating enzyme E2-17 kDa 1, Ubiquitin-protein ligase D1

Synonyms: UbcH5a, Ubiquitin conjugating enzyme H5a, Ubiquitin conjugating enzyme

Background Information: UbcH5a is highly homologous to the S. cerevisiae Ubc4/5 family of E2 enzymes demonstrated to be essential for degradation of regulatory and abnormal proteins. UbcH5a, together with UbcH5b and UbcH5c, are the most active class of E2 enzymes in cell extracts and are associated with regulation of a number of transcription factors. Specifically, UbcH5a stimulates the conjugation of ubiquitin to the tumor suppressor p532. Useful for in vitro ubiquitinylation reactions. Typical enzyme concentration to support conjugation in vitro is 100 nM to 1 µM depending upon conditions.

Reconstitution Instructions: N/A

NCBI Gene Symbol: UB2D1

Gene ID: 7321

NCBI Accession: P51668