TREM2, human recombinant

TREM2, human recombinant is available at Gentaur for Next week delivery.

Involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines

Biomolecule/Target: TREM2

Alternates names: Triggering receptor expressed on myeloid cells 2, Trem2a, Trem2b, Trem2c

Synonyms: Triggering receptor expressed on myeloid cells 2, Trem2a, Trem2b, Trem2c

Background Information: TREM2 is a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The protein functions in immune response and maybe involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. Recombinant human TREM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: TREM2

Gene ID: 54209

NCBI Accession: Q9NZC2