TPI1, human recombinant

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SKU:
P1097-50
€185
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Description

TPI1, human recombinant is available at Gentaur for Next week delivery.

Involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis

Biomolecule/Target: TPI1

Alternates names: TPI1 human Recombinant , Recombinant human TPI1, TPI1, TPI1 Recombinant, Human TPI1, Human Recombinant TPI1, TPI1, TPI1 Recombinant, Human TPI1, Human TPI1, human TPI1, TPI1 Recombinant protein, TPI1 human protein, Human TPI1 protein, Human TPI1 Recombinant protein, TPI1 protein, TPI1 protein, TPI1 Recombinant protein, triosephosphate isomerase, TPI

Synonyms: triosephosphate isomerase, TPI

Background Information: TPI1 (Triosephosphate isomerase) belongs to the triosephosphate isomerase family. TPI1 catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency). TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. Recombinant human TPI1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: TPI1

Gene ID: 7167

NCBI Accession: P60174

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Additional Information

Size:
50 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
Measured by the ability to convert 1.0 umole of D-glyceraldehyde-3-phosphate to dihydroxyacetone phosphate per minute at pH 7.5 at 25C.
Biological activity:
Specific activity is > 3000 units/mg, in which one unit will convert 1.0 umole of D-glyceraldehyde-3-phosphate to dihydroxyacetone phosphate per minute at pH 7.5 at 25C.
Results:
>3000 units/mg
Molecular Weight:
28.8 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
0.5 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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