Thrombospondin, human recombinant

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SKU:
4805-50
€185
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Description

Thrombospondin, human recombinant is available at Gentaur for Next week delivery.

A secreted protein with antiangiogenic abilities

Biomolecule/Target:

Alternates names: Thrombospondin-1, THBS1, TSP, TSP1, THBS, THBS-1

Synonyms: Thrombospondin-1, THBS1, TSP, TSP1, THBS, THBS-1

Background Information: Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been used as a potential regulator of tumor growth and metastasis. TSP expression is highly regulated by different hormones and cytokines and is developmentally controlled. TSP stimulates the growth of Vascular smooth muscle cells and human foreskin fibroblasts, a combination of IFN-γ and TNF-α inhibits TSP production in these cells. Recombinant Human Thrombospondin is glycosylated with N-linked sugars and produced using baculovirus vectors in insect cells. Human Thrombospondin is purified by proprietary chromatographic techniques.

Reconstitution Instructions: Reconstitute with water at the concentration 0.1 mg/ml.

NCBI Gene Symbol: TSP1

Gene ID: 7057

NCBI Accession: P07996

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
Baculovirus (Sf9 insect cells)
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
180 kDa in reducing gel
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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