Thioredoxin isoform 1 (Trx), Active, Human Recombinant

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SKU:
P1039-100
£135.37
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Description

Thioredoxin isoform 1 (Trx), Active, Human Recombinant is available at Gentaur for Next week delivery.

A protein involved in redox signaling

Biomolecule/Target: Trx

Alternates names: TXN, TRX, TRX1, Thioredoxin 1

Synonyms: TXN, TRX, TRX1, Thioredoxin 1

Background Information: Thioredoxin (Trx) is a disulfide reductase that reduces disulfide bonds into thiol groups through a thiol-disulfide exchange with its target proteins to regulate oxidative stress and redox signaling. Trx activity is dependent on NADPH and Thioredoxin Reductase’s (TrxR) ability to reduce it at Cysteine 32 and Cysteine 35.

Reconstitution Instructions: Reconstitute in deionized water.

NCBI Gene Symbol: TXN

Gene ID: 7295

NCBI Accession: P10599

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
Measured by its ability to reduce FITC-labeled oxidized glutathione (FITC-GSSG-FITC) to FITC-labeled reduced glutathione (FITC-GSH).
Biological activity:
This enzyme has activity ≥20 mU/mg based on its ability to reduce FITC-labeled oxidized glutathione (FITC-GSSG-FITC) to FITC-labeled reduced glutathione (FITC-GSH).
Results:
Enzymatic activity is ≥20 U/mg
Molecular Weight:
14.5 kDa (130 aa)
Storage Temperature:
4°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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