TGF-beta1, human recombinant

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SKU:
4342-500
£135.37
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Description

TGF-beta1, human recombinant is available at Gentaur for Next week delivery.

A protein that controls proliferation, cellular differentiation, & other functions in most cells

Biomolecule/Target: TGF-beta 1

Alternates names: Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor

Synonyms: Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor

Background Information: TGF-β1 (Transforming Growth Factor-β1) is a member of the superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-β1 is a 25.0 kDa protein containing two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

Reconstitution Instructions: Reconstitution in H₂O to a concentration of 50 ug/ml (e.g., 5 ug/100 μl) will yield a solution of 1 mM citrate buffer (pH 3.5). The solution can then be stored at 4°C for 1 month. It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at –20°C.

NCBI Gene Symbol: TGFB1

Gene ID: 7040

NCBI Accession: P01137

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Additional Information

Size:
500 μg
Adwords:
yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
CHO cells
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ as determined by the ability of TGF-β1 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is <0.05 ng/ml, corresponding to a specific activity of >2 x 10⁷ units/mg.
Results:
<0.05 ng/ml
Molecular Weight:
25.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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