Description
TGF-beta1, human recombinant is available at Gentaur for Next week delivery.
A protein that controls proliferation, cellular differentiation, & other functions in most cells
Biomolecule/Target: TGF-beta 1
Alternates names: Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor
Synonyms: Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor
Background Information: TGF-β1 (Transforming Growth Factor-β1) is a member of the superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-β1 is a 25.0 kDa protein containing two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
Reconstitution Instructions: Reconstitution in H₂O to a concentration of 50 ug/ml (e.g., 5 ug/100 μl) will yield a solution of 1 mM citrate buffer (pH 3.5). The solution can then be stored at 4°C for 1 month. It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at –20°C.
NCBI Gene Symbol: TGFB1
Gene ID: 7040
NCBI Accession: P01137
Additional Information
Size: |
500 μg |
Adwords: |
yes |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
CHO cells |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The ED₅₀ as determined by the ability of TGF-β1 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is <0.05 ng/ml, corresponding to a specific activity of >2 x 10⁷ units/mg. |
Results: |
<0.05 ng/ml |
Molecular Weight: |
25.0 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |