TGF-alpha, human recombinant

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SKU:
4339-20
£135.37
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Description

TGF-alpha, human recombinant is available at Gentaur for Next week delivery.

A growth factor upregulated in some cancers

Biomolecule/Target: TGF-alpha

Alternates names: Transforming Growth Factor-α, Sacroma growth factor, TGF-type I, ETGF

Synonyms: Transforming Growth Factor-α, Sacroma growth factor, TGF-type I, ETGF

Background Information: Transforming Growth Factor-α (TGF-α) stimulates the proliferation of a wide range of epidermal and epithelial cells. TGF-α has been shown to play a role in the autocrine growth of certain transformed cells. Human TGF-α is a 5.5 kDa protein containing 50 amino acid residues.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use. For most in vitro applications, TGF-α exerts its biological activity in the concentration range of 0.5 to 25 ng/ml.

NCBI Gene Symbol: TGFA

Gene ID: 7039

NCBI Accession: P01135

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Additional Information

Size:
20 μg
Adwords:
yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ as determined by the dose-dependent stimulation of proliferation of Balb-c 3T3 cells is <0.2 ng/ml, corresponding to a specific activity of >5 x 10⁶ units/mg.
Results:
<0.2 ng/ml
Molecular Weight:
5.5 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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