Description
TGF-β3, Mouse Recombinant is available at Gentaur for Next week delivery.
Plays an important role in wound repair/scarring, osteoblast proliferation, chemotaxis, and collagen synthesis
Biomolecule/Target: TGF-beta-1
Alternates names: Transforming growth factor beta-3
Synonyms: Transforming growth factor beta-3
Background Information: The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-β isoforms (TGF-β1, -β2 and –β3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-β3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-β3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis. Recombinant mouse TGF-β3 is a non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains, with a total molecular weight of 25.5 kDa.
Reconstitution Instructions: N/A
NCBI Gene Symbol: TGF-beta-1
Gene ID: 21803
NCBI Accession: P04202
Additional Information
Size: |
500 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Mouse |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein |
Activity (Specifications/test method): |
The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than 0.05 ng/mL. |
Biological activity: |
The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than 0.05 ng/mL. |
Results: |
N/A |
Molecular Weight: |
25.5 kDa. |
Storage Temperature: |
4°C |
Shelf Life: |
12 months |
Concentration: |
0.25 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |