TGF-β3, Mouse Recombinant

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SKU:
7588-500
€185
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Description

TGF-β3, Mouse Recombinant is available at Gentaur for Next week delivery.

Plays an important role in wound repair/scarring, osteoblast proliferation, chemotaxis, and collagen synthesis

Biomolecule/Target: TGF-beta-1

Alternates names: Transforming growth factor beta-3

Synonyms: Transforming growth factor beta-3

Background Information: The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-β isoforms (TGF-β1, -β2 and –β3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-β3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-β3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis. Recombinant mouse TGF-β3 is a non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains, with a total molecular weight of 25.5 kDa.

Reconstitution Instructions: N/A

NCBI Gene Symbol: TGF-beta-1

Gene ID: 21803

NCBI Accession: P04202

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Additional Information

Size:
500 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein
Activity (Specifications/test method):
The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than 0.05 ng/mL.
Biological activity:
The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than 0.05 ng/mL.
Results:
N/A
Molecular Weight:
25.5 kDa.
Storage Temperature:
4°C
Shelf Life:
12 months
Concentration:
0.25 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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