TFF-2, human recombinant

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SKU:
4745-20
$719.07
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Description

TFF-2, human recombinant is available at Gentaur for Next week delivery.

A protein which protects and stabilizes the gastric mucus layer

Biomolecule/Target:

Alternates names: Trefoil Factor 2, Spasmolytic polypeptide (SP), Spasmolysin

Synonyms: Trefoil Factor 2, Spasmolytic polypeptide (SP), Spasmolysin

Background Information: The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma. Recombinant human TFF2 is a 12.0 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffers

NCBI Gene Symbol: TFF2

Gene ID: 7032

NCBI Accession: Q03404

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Additional Information

Size:
20 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 µg/ml.
Results:
1.0-10.0 µg/ml
Molecular Weight:
12.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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