sTNF-RI, human recombinant

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SKU:
4348-20
$183
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Description

sTNF-RI, human recombinant is available at Gentaur for Next week delivery.

Mediates TNF-alpha induced sickness behavior & neurotoxic processes

Biomolecule/Target: sTNF-RI

Alternates names: Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, TNF-R1, TNF-RI, TNFR-I, p60, p55, CD120a, TNFRSF1A, TNFAR, TNFR1, FPF, TBP1, TNF-R, p55-R, TNFR55, TNFR60, TNF-R-I, TNF-R55, MGC19588,

Synonyms: Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, TNF-R1, TNF-RI, TNFR-I, p60, p55, CD120a, TNFRSF1A, TNFAR, TNFR1, FPF, TBP1, TNF-R, p55-R, TNFR55, TNFR60, TNF-R-I, TNF-R55, MGC19588,

Background Information: Tumor Necrosis Factor receptor type I (TNF-RI) is also referred as p60. The p60 form of the receptor is primarily expressed on epithelial cells. Recombinant Human soluble TNF receptor Type I (sTNF-RI) is a 18.3 kDa protein containing 162 amino acid residues comprising the extra Cellular domain of TNF Receptor Type I.

Reconstitution Instructions: Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers

NCBI Gene Symbol: TNR1A

Gene ID: 7132

NCBI Accession: AAA36756

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Additional Information

Size:
20 μg
Adwords:
yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The biological activity of sTNF-RI was determined by its inhibitory effect of the TNF-α mediated cytotoxicity in murine L-929 cells. The ED₅₀ for the effect in the presence of 0.25 ng/ml of recombinant TNF-α, is 0.05 mg/ml.
Results:
0.05 μg/ml.
Molecular Weight:
18.3 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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