Description
Recombinant SARS-CoV-2 NSP7 is available at Gentaur for Next week delivery.
Plays an important role in viral replication
Biomolecule/Target:
Alternates names: SARS-CoV-2 NSP7; COVID-19 NSP7; 2019-nCoV NSP7; Non-Structural Protein 7; nsp7
Synonyms: SARS-CoV-2 NSP7; COVID-19 NSP7; 2019-nCoV NSP7; Non-Structural Protein 7; nsp7
Background Information: The replication of Coronavirus is operated by multiple non-structural proteins (nsps). The viral genomic RNA is translated from two open reading frames (ORFs), ORF1a and ORF1b. The encoded replicase polyproteins, pp1a and pp1ab, are further processed to produce nsps. NSP7 plays an important role in the transcription and replication of the viral RNA genome. NSP7 is a component of the coronavirus replicase polyprotein that forms a replication complex. It can form a dimer with NSP8 and subsequently assembles into a large hexadecameric structure, which participates in viral replication by acting as a primase. The NSP12-NSP7-NSP8 subcomplex is found to be the minimal core component for the synthesis of coronavirus RNA.
Reconstitution Instructions:
NCBI Gene Symbol:
Gene ID:
NCBI Accession: YP_009725303.1
Additional Information
Size: |
50 μg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Coronavirus |
Recombinant: |
1 |
Source: |
E.coli |
Purity by SDS-PAGE: |
≥ 95% by SDS-PAGE |
Biological activity: |
Activity was validated through an enzymatic assay of NSP7-NSP8/NSP12 |
Molecular Weight: |
The predicted molecular weight is 11.5 kDa. The protein migrates at < 14.4 kDa under reducing conditions. |
Storage Temperature: |
-70°C |
Shelf Life: |
6 months |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |