Recombinant Murine Interleukin-27/p28 (IL-30)

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SKU:
4187-1000
£135.37
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Description

Recombinant Murine Interleukin-27/p28 (IL-30) is available at Gentaur for Next week delivery.

A regulator of B- and T-lymphocyte's activities

Biomolecule/Target: IL-27/p28

Alternates names: Interleukin-30, IL-30, IL-27/p28, p28, Interleukin-27, Interleukin-27/p28, IL-27, Interleukin-27 subunit α, IL-27 subunit α, IL27-A, Il27, Il27a, IL-27p28.

Synonyms: Interleukin-30, IL-30, IL-27/p28, p28, Interleukin-27, Interleukin-27/p28, IL-27, Interleukin-27 subunit α, IL-27 subunit α, IL27-A, Il27, Il27a, IL-27p28.

Background Information: The p28 subunit of IL-27 (IL-27/p28), also known as Interleukin-30 (IL-30), is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), p28 forms a heterodimer known as IL-27. p28 is thought to be a pro-inflammatory cytokine inducing immuno-modulatory effects, but the details of these effects are currently unclear and research is focused on delineating its specific biological functions. Recombinant mouse p28 is a non-glycosylated protein, containing 207 amino acids, with a molecular weight of 23.7 kDa.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-0.5 mg/ml. The solution can then be diluted into other aqueous buffers

NCBI Gene Symbol: IL27

Gene ID: 246779

NCBI Accession: Q8K3I6

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Additional Information

Size:
1 mg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥97%
Assay:
SDS-PAGE
Purity:
≥97%
Assay 2:
HPLC
Endotoxin Level:
<0.01 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
Measured by dose-dependent inhibition of TGF-β & Il-6-induced IL-17A expression in mouse CD4 splenocytes. 50 ng/ml of mouse p28 is capable of inhibiting >25% of Il-17A expression in this assay.
Results:
50 ng/ml
Molecular Weight:
23.7 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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