PNP, human recombinant

PNP, human recombinant is available at Gentaur for Next week delivery.

Catalyzes the reversible phosphorolysis of ribonucleosides and 2'-deoxyribonucleosides

Biomolecule/Target: PNP

Alternates names: Purine nucleoside phosphorylase, NP, Inosine phosphorylase, PRO1837, PUNP

Synonyms: Purine nucleoside phosphorylase, NP, Inosine phosphorylase, PRO1837, PUNP

Background Information: PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2'-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. Recombinant human PNP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques

Reconstitution Instructions: N/A

NCBI Gene Symbol: PNP

Gene ID: 4860

NCBI Accession: P00491