Description
PI3K (p85⍺) Protein is available at Gentaur for Next week delivery.
Intracellular signal transducer enzyme
Biomolecule/Target:
Alternates names: PI3K (p85⍺) Protein, PI3K, PI3 kinase
Synonyms: PI3K (p85⍺) Protein, PI3K, PI3 kinase
Background Information: The PI3K comprises of a 110 kDa catalytic subunit and a 85 kDa regulatory subunit. A number of isoforms of the 110 kDa catalytic subunit and the 85 kDa regulatory subunit exist in cells. p85αmodulates the interaction between PI3K and platelet-derived growth factor receptor (1). Furthermore, estrogen receptor isoform ER-alpha binds in a ligand-dependent manner to the p85α regulatory subunit of PI3K. Stimulation with estrogen increases ER-alpha-associated PI3K activity, leading to the activation of protein kinase B/AKT and endothelial nitric oxide synthase (eNOS) (2).
Reconstitution Instructions: N/A
NCBI Gene Symbol: PIK3R1
Gene ID: 5295
NCBI Accession: NM_181523
Additional Information
Size: |
5 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Recombinant: |
Yes |
Source: |
Baculovirus (Sf9 insect cells) |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
86.0 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
0.2 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |