PF-4/CXCL4, murine recombinant

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SKU:
7187-50
£135.37
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Description

PF-4/CXCL4, murine recombinant is available at Gentaur for Next week delivery.

Involved in inhibition of angiogenesis

Biomolecule/Target: CXCL4

Alternates names: Platelet Factor-4, CXCL4, Oncostatin A, Ironplact

Synonyms: Platelet Factor-4, CXCL4, Oncostatin A, Ironplact

Background Information: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant murine PF-4 is an 8.2 kDa protein containing 76 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: CXCL4

Gene ID: 56744

NCBI Accession: Q9Z126

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
< 0.1 ng/μg of protein (<1EU/μg).
Activity (Specifications/test method):
Determined by its ability to chemoattract human neutrophils using a concentration
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