PCNA, Human Recombinant

PCNA, Human Recombinant is available at Gentaur for Next week delivery.

A processivity factor for DNA polymerase δ

Biomolecule/Target:

Alternates names: Proliferating cell nuclear antigen, MGC8367, Proliferating cell nuclear antigen, Proliferating cell nuclear antigen, PCNA

Synonyms: Proliferating cell nuclear antigen, MGC8367, Proliferating cell nuclear antigen, Proliferating cell nuclear antigen, PCNA

Background Information: PCNA (Proliferating Cell Nuclear Antigen) is found in the nucleus and is a cofactor of DNA polymerase delta. This protein is associated with DNA synthesis and repair. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. It appears during late G1- phase, Sphase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA may be induced by UV irradiation, growth factors and eventually by neighbouring tumours. Recombinant human PCNA, was expressed in E. coli and purified by conventional chromatography techniques.

Reconstitution Instructions:

NCBI Gene Symbol: PCNA

Gene ID: 5111

NCBI Accession: P12004