Description
OryzaExp™ Alpha-1 Antitrypsin, Human Recombinant is available at Gentaur for Next week delivery.
An acute-phase plasma protein
Biomolecule/Target:
Alternates names: Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, AAT, PI
Synonyms: Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, AAT, PI
Background Information: Alpha 1 Antitrypsin is an acute-phase plasma protein found at 290 mg per 100 ml. It functions as a serine protease inhibitor with targets like elastase, plasmin, collagenase, thrombin, leucocyte proteases, trypsin, chymotrypsin, and plasminogen activator. Clinically, its deficiency is associated with two major diseases: pulmonary emphysema and early onset/juvenile hepatic cirrhosis. It is elevated in inflammatory conditions, malignancies, liver disease and pregnancy and also after surgical trauma and use of oral contraceptives. The simultaneous quantitative determination of alpha-1-PI and ceruloplasmin permits differential diagnosis of liver afflictions. Rise in alpha 1 antitrypsin occurs as an acute phase response to tissue necrosis and inflammatio
Reconstitution Instructions: Reconstitute in sterile PBS
NCBI Gene Symbol: SERPINA1
Gene ID: 5265
NCBI Accession: AAB59375
Additional Information
Size: |
100 μg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
N/A |
Gene Source: |
Human |
Recombinant: |
True |
Source: |
Orzya sativa |
Purity by SDS-PAGE: |
> 95% |
Endotoxin Level: |
≤1EU/ug |
Activity (Specifications/test method): |
3~5 mg OsrAAT inhibit 1 mg PPE (pancreatic porcine elastase) with 10.8 units per mg protein. |
Molecular Weight: |
43.2 KDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |