NP-1, Human Recombinant

NP-1, Human Recombinant is available at Gentaur for Next week delivery.

In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells.

Biomolecule/Target: NP-1

Alternates names: Neutrophil Peptide-1, alpha Defensin-1, HNP-1, Cryptdin, Vascular endothelial cell growth factor 165 receptor, CD304, NRP, VEGF165R, NRP1, neuronal pentraxin-1, NP1, NPTX1

Synonyms: Neutrophil Peptide-1, alpha Defensin-1, HNP-1, Cryptdin, Vascular endothelial cell growth factor 165 receptor, CD304, NRP, VEGF165R, NRP1, neuronal pentraxin-1, NP1, NPTX1

Background Information: Defensins (α and β) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins which include NP-1, NP-2 and NP-3, are distinguished from the β-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human NP-1 is a 3.4 kDa protein containing 30 amino acid residues.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: NRP1

Gene ID: 8829

NCBI Accession: O14786