Description
NMNAT1, human recombinant is available at Gentaur for Next week delivery.
Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP.
Biomolecule/Target: NMNAT1
Alternates names: Nicotinamide Mononucleotide Adenylyl-transferase 1, NMN Adenylyltransferase 1; NaMN Adenylyltransferase 1; EC 2.7.7.1.
Synonyms: Nicotinamide Mononucleotide Adenylyl-transferase 1, NMN Adenylyltransferase 1; NaMN Adenylyltransferase 1; EC 2.7.7.1.
Background Information: This is the nuclear NMNAT isoform. It catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. It interacts with PARP-1/ARTD1. It protects against axonal degeneration following mechanical or toxic insults. It is widely expressed.
Reconstitution Instructions: N/A
NCBI Gene Symbol: NMNAT1
Gene ID: 64802
NCBI Accession: Q9HAN9
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
≥ 5U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1 µmol of NAD+ per min. |
Results: |
≥ 5U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1 µmol of NAD+ per min. |
Molecular Weight: |
~33.3 kDa (monomer). Human full-length NMNAT1 (aa 1-279) is fused at the N-terminus to a His-tag. |
Storage Temperature: |
-20°C |
Shelf Life: |
6 months |
Concentration: |
1 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |