MIA-2, human recombinant

MIA-2, human recombinant is available at Gentaur for Next week delivery.

Potential role in the pathophysiology of liver disease

Biomolecule/Target:

Alternates names: Melanoma inhibitory activity protein 2, Melanoma inhibitory activity protein 2

Synonyms: Melanoma inhibitory activity protein 2

Background Information: MIA2 performs as a tumour suppressor in hepatocellular carcinoma. MIA2 is a novel acute phase protein which its expression is found in the liver and reacts to liver damage in chronic liver diseases and is considerably higher in severe fibrosis patients . MIA2 is induced by IL6, TGF-b and conditioned medium from activated hepatic stellate cells. MIA2 is is mainly expressed in hepatocytes. MIA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain consisting of 101 amino having a total molecular mass of 11.5 kDa. The MIA2 is purified by proprietary chromatographic techniques.

Reconstitution Instructions: Reconstitute in sterile H₂O at >100 µg/ml. Reconstituted MIA2 should be stored in working aliquots at -20°C.

NCBI Gene Symbol: MIA2

Gene ID: 117153

NCBI Accession: Q96PC5