Description
MET, Active is available at Gentaur for Next week delivery.
A proto-oncogene
Biomolecule/Target:
Alternates names: MET, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, Short name=SF receptor, Tyrosine-protein kinase Met
Synonyms: MET
Background Information: MET is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kd (α) and 145 kd (β). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue (1). Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers and has been shown to be involved in tumor cell migration and invasion (2).
Reconstitution Instructions: N/A
NCBI Gene Symbol: MET
NCBI Accession: X96786
Additional Information
Size: |
5 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Recombinant: |
Yes |
Source: |
Baculovirus (Sf9 insect cells) |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
The specific activity of MET was determined to be 46 nmol /min/mg as per activity assay protocol. |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
74.0 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
0.1mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |