MEC/CCL28, murine recombinant

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SKU:
7171-50
£135.37
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Description

MEC/CCL28, murine recombinant is available at Gentaur for Next week delivery.

Chemoattracts resting CD4, CD8 T cells and eosinophils

Biomolecule/Target: CCL28

Alternates names: Mucosae-associated Epithelial Chemokine, CCL28, CCK-1

Synonyms: Mucosae-associated Epithelial Chemokine, CCL28, CCK-1

Background Information: MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor and chemoattracts resting CD4, CD8 T cells and eosinophils. MEC contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MEC is a 12.6 kDa protein containing 111 amino acid residues.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: CCL28

Gene ID: 56838

NCBI Accession: Q9JIL2

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Murine
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
< 0.1 ng/μg of protein (<1EU/μg).
Activity (Specifications/test method):
Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml.
Biological activity:
Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml.
Results:
N/A
Molecular Weight:
12.6 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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