MDC/CCL22, murine recombinant

MDC/CCL22, murine recombinant is available at Gentaur for Next week delivery.

Chemoattracts monocytes, dendritic cells and NK cells

Biomolecule/Target: CCL22

Alternates names: Macrophage-Derived Chemokine, CCL22, STCP-1, ABCD-1

Synonyms: Macrophage-Derived Chemokine, CCL22, STCP-1, ABCD-1

Background Information: MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant murine MDC is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: CCL22

Gene ID: 20299

NCBI Accession: O88430