MCP-5/CCL12, murine recombinant

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SKU:
7168-50
£135.37
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Description

MCP-5/CCL12, murine recombinant is available at Gentaur for Next week delivery.

Chemoattracts / activates monocytes, activated T cells, basophils, NK cells, and immature dendritic cells

Biomolecule/Target: CCL12

Alternates names: Monocyte Chemotactic Protein-5, CCL12

Synonyms: Monocyte Chemotactic Protein-5, CCL12

Background Information: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-5 is a 9.3 kDa protein containing 82 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: CCL12

Gene ID: 20293

NCBI Accession: Q62401

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Murine
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
< 0.1 ng/μg of protein (<1EU/μg).
Activity (Specifications/test method):
Determined by its ability to chemoattract human peripheral blood monocytes using
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