LIX (CXCL6), Murine Recombinant

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SKU:
P1293-5
€185
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Description

LIX (CXCL6), Murine Recombinant is available at Gentaur for Next week delivery.

Chemoattractant for neutrophils

Biomolecule/Target: LIX (CXCL6)

Alternates names: CXCL6, GCP-2 (human), Granulocyte Chemotactic Protein-2

Synonyms: CXCL6, GCP-2 (human), Granulocyte Chemotactic Protein-2

Background Information: LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant murine LIX is a 9.8 kDa protein containing 92 amino acid residues.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to aliquot and store at -20°C to -80°C.

NCBI Gene Symbol:

Gene ID:

NCBI Accession:

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Additional Information

Size:
5 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Murine
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥ 98%
Assay:
SDS-PAGE
Endotoxin Level:
<0.1 EU/μg
Biological activity:
Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml
Molecular Weight:
9.8 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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