Kallikrein-2, Human Recombinant

Kallikrein-2, Human Recombinant is available at Gentaur for Next week delivery.

Trypsin-like serine protease that selectively cleaves at arginine residues

Biomolecule/Target:

Alternates names: Glandular kallikrein-1, hGK-1, Tissue kallikrein-2

Synonyms: Glandular kallikrein-1, hGK-1, Tissue kallikrein-2

Background Information: KLK2 is a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. KLK2 is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. Recombinant human KLK2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Reconstitution Instructions:

NCBI Gene Symbol: KLK2

Gene ID: 3817

NCBI Accession: P20151